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Cialis vs Viagra - A Brief History

A Happy Accident

It all began in 1993, when the Icos Corporation in Washington, began testing a PDE5 enzyme prohibitor called IC351. It was the exact scientific process that improves erective dysfunction in men but unfortunately they were unaware of this use for the drug they were testing.

Your Boner and the Early 1990's

They conducted tests on patients in 1994 and clinical trials in 1995 for enzyme prohibition. It was only in 1997 that Icos began testing their compound IC351 for the treatment of erectile dysfunction. Then in 1998, Icos and the pharmaceutical company Eli Lilly and Co amalgamated and continued tests until in 2002, they showed evidence that proved not only that the medication was effective in treating erectile dysfunction but more importantly for them, they proved that the drug remained active in the body for up to 36 hours. The compound IC351 was then given the name Cialis. They presented their findings and in 2002, the drug was approved for sale in Europe and a patent for tadalafil or Cialis was granted to the ICOS Corporation by the US Patent and Trademark Office on January 21, 2003. The company was then approved to release the medication in the United States. If Lilly had tested their chemical compound IC351 for erectile dysfunction back in 1993, they would have realized how effective it was and history may have been re-written.

Viagra was Originally Heart Medication

Instead, Pfizer were doing their own testing and in 1994, during clinical trials for sildenafil citrate or Viagra as a heart medicine, they accidentally discovered that the compound was causing erections to occur in many of the men who were taking the drug. They were not doing any tests for men suffering from erectile dysfunction at all, they were doing tests on hypertension and simply stumbled upon the erection effect of the drug during tests. In the process, one of the most renowned drugs around the world was discovered. Viagra was patented in 1996 and approved by the FDA, as the first medication for the treatment of ED in the United States on March 27, 1998.

Big Money

Pfizer, the manufacturer of Viagra, enjoyed a monopoly over the ED market for more than five years. In 2000, sales of Viagra had a lion’s share of more than 90% of the global ED medication market. It was not until the sale of Levitra was approved by the FDA in August 2003 and then Cialis in November 2003, that the market opened up. Pfizer reportedly made over one billion dollars in the first year that the medication also known as ‘blue diamonds’ was released onto the market. By 2008, that sales figure had almost doubled.

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